The induction and regulation of innate host defenses are believed to affect the earliest stages of pathogen entry, colonization, survival, replication and disease kinetics, as well as disease resistance, transmission and ultimately human and animal health. Understanding the mechanisms by which pathogens usurp or alter these responses will be important in inducing earlier, more potent and possibly more durable immunity.
Immunology field is supported by recent and ongoing advances in genomics, molecular biology, proteomics, microbiology, cellular biology, nanotechnology, epidemiology, animal and mathematical modelling. These tools and the development of others appear necessary for beginning to dissect the major gaps in our understanding of how these pathogens can avoid, evade, survive, lay dormant and/or be transmitted in the host despite evidence of the host mounting an immune response against it.
The First German-Argentinean Workshop on "Pathogen invasion and immune evasion" is designed to explore different mechanisms of virulence within these microbes and their poorly characterized interactions with the host defense systems of the host.
The participants will be in charge with the job of identifying those knowledge gaps, research priority areas, and research objectives that will advance the future development of new approaches and technologies against emerging pathogens, many of which fall into the category of annually re-occurring and chronic-active, -latent agents that evade the host immune response.